The stakes couldn’t be higher for the men from Lyon. After a disappointing away loss in the first encounter, head coach Paulo Fonseca has made bold changes to his starting lineup. The return of suspended defender Moussa Niakhaté is complemented by the inclusion of exciting young forwards Malick Fofana and Ernest Nuamah in an attempt to overturn the deficit.

Sparta Prague, meanwhile, hold a slender one-goal advantage following their victory in the Czech capital. Lyon had initially taken the lead in Prague through an unfortunate own goal, but the hosts fought back with two goals in six minutes, compounded by Corentin Tolisso’s missed penalty in the 67th minute. Now, the Olympique Lyonnais must dig deep and secure a victory to force extra time or penalties.

Key storylines ahead of the clash

Lyon’s uphill task

Lyon finished fourth in Ligue 1 last season with a record of 18 wins, 6 draws, and 10 losses, securing their spot in the third qualifying round with 60 points—just one point behind Lille. However, they enter this match having yet to play a single competitive game in the new Ligue 1 campaign. This encounter represents only their second competitive outing after the first leg against Sparta Prague, making their preparation far from ideal.

Sparta Prague’s form dip

The Czech side, runners-up in their domestic league with 76 points (four behind Slavia Prague), arrive in Lyon on the back of a mixed start to the season. Following their triumphant first leg, they suffered a 2-0 defeat to Mladá Boleslav in their most recent league match. This follows an earlier 3-1 loss to Zbrojovka Brno in the opening fixture, casting a shadow over their domestic form.

European pedigree on display

Both teams earned their spots in this high-stakes qualifier through strong campaigns last season. Lyon’s fourth-place finish in Ligue 1 and Sparta Prague’s second-place finish in the Czech First League demonstrate their competitiveness on the European stage. The winner of this tie will advance to face either Fenerbahçe or Sturm Graz in the playoff round.